Contrasting Histopathology and Crystal Deposits in Kidneys of Idiopathic Stone Formers Who Produce Hydroxy Apatite, Brushite, or Calcium Oxalate Stones
نویسندگان
چکیده
منابع مشابه
Role of interstitial apatite plaque in the pathogenesis of the common calcium oxalate stone.
By using intraoperative papillary biopsy material from kidneys of idiopathic calcium oxalate, intestinal bypass for obesity, brushite, cystine, and distal renal tubular acidosis stone formers during percutaneous nephrolithotomy, we have determined that idiopathic calcium oxalate stone formers appear to be the special case, although the most commonly encountered one, in which stones form externa...
متن کاملCrystal-associated nephropathy in patients with brushite nephrolithiasis.
BACKGROUND We have biopsied the renal cortex and papillae of patients who form brushite renal stones asking if this unusual stone type is associated with specific tissue changes. We contrasted these with biopsies of 15 calcium oxalate stone formers, three stone formers with intestinal bypass, and four normal subjects. METHODS We studied all ten brushite stone formers treated with percutaneous...
متن کاملDistinguishing characteristics of idiopathic calcium oxalate kidney stone formers with low amounts of Randall's plaque.
BACKGROUND Overgrowth of calcium oxalate on Randall's plaque is a mechanism of stone formation among idiopathic calcium oxalate stone-formers (ICSFs). It is less clear how stones form when there is little or no plaque. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Participants were a consecutive cohort of ICSFs who underwent percutaneous nephroscopic papillary mapping in the kidney or kidneys...
متن کاملPathophysiology-based treatment of idiopathic calcium kidney stones.
Idiopathic calcium oxalate (CaOx) stone-formers (ICSFs) differ from patients who make idiopathic calcium phosphate (CaP) stones (IPSFs). ICSFs, but not IPSFs, form their stones as overgrowths on interstitial apatite plaque; the amount of plaque covering papillary surface is positively correlated with urine calcium excretion and inversely with urine volume. The amount of plaque predicts the numb...
متن کاملNephrocalcinosis in Calcium Stone Formers Who Do Not have Systemic Disease.
PURPOSE Nephrocalcinosis is commonly present in primary hyperparathyroidism, distal renal tubular acidosis and medullary sponge kidney disease. To our knowledge it has not been studied in patients with calcium phosphate stones who do not have systemic disease. MATERIALS AND METHODS We studied patients undergoing percutaneous nephrolithotomy who had calcium phosphate or calcium oxalate stones ...
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ژورنال
عنوان ژورنال: The Anatomical Record
سال: 2014
ISSN: 1932-8486
DOI: 10.1002/ar.22881